Data in the literature suggests that elevated Lp(a) contributes to coronary artery disease. This case study documents the use of ascorbic acid, amino acids lysine and proline, an ayurvedic herb gum guggulu, pure crystaline niacin , and guar gum in lowering Lp(a). These natural substances were well tolerated and each lowered Lp(a) significantly. In this study (32 months duration) one of the above mentioned substances and/or an increase or change in dosage was given approximately every two months to a 62 year old female with extremely elevated familial Lp(a). Blood lipids were drawn and results were recorded before changes were made. At the end of 32 months Lp(a) was reduced by 8l points or 63%. Significant re gression of coronary artery blockages was documented by a Board Certified Cardiologist who analyzed two angiograms performed one and half years apart, the latter performed 19 months after the study began. It was also observed that Lp(a) decreased directly in relation to the decrease in LDL. Research with clinical studies is recommended to test the efficacy of the above-mentioned nutritional substances in lowering Lp(a) and in both lessening the risk of coronary artery disease and in regressing already existing disease. This is especially crucial for those families with a strong history of familial coronary artery disease and elevated Lp(a).

http://orthomolecular.org/library/jom/1996/articles/1996-v11n03-p173.shtml